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Randomized Controlled Trial
A controlled clinical trial that randomly (by chance) assigns participants to two or more groups. There are various methods to randomize study participants to their groups.
Example:
Adapted from Study Designs; in NICHSR Introduction to Health Services Research: a Self-Study Course
Cohort Study (Prospective Observational Study)
A clinical research study in which people who presently have a certain condition or receive a particular treatment are followed over time and compared with another group of people who are not affected by the condition.
Example:
Adapted from Study Designs; in NICHSR Introduction to Health Services Research: a Self-Study Course
Case-control Study
Case-control studies begin with the outcomes and do not follow people over time. Researchers choose people with a particular result (the cases) and interview the groups or check their records to ascertain what different experiences they had. They compare the odds of having an experience with the outcome to the odds of having an experience without the outcome.
Example:
Adapted from Study Designs; in NICHSR Introduction to Health Services Research: a Self-Study Course
Cross-sectional study
The observation of a defined population at a single point in time or time interval. Exposure and outcome are determined simultaneously.
Example:
Adapted from Study Designs; in NICHSR Introduction to Health Services Research: a Self-Study Course
What is an empirical study?
View a short video about empirical studies and how they differ from others at the link below:
The Methods section of a paper can tell you what type of paper you're reading - is it an empirical study with original data, or is it a review of other papers? Here are two examples to show the difference:
This clinical trial shows a methodology that includes recruiting participants within a particular demographic, assigning study groups and applying different experimental conditions to each, and collecting data from these groups to reach a conclusion:
This systematic review, in contrast, shows a methodology that includes searching databases for particular terms, in order to find previous scientific papers according to given criteria: